Favipiravir as RNA Polymerase Dependent (Rdrp) in COVID-19
Abstract
Coronavirus disease 2019 or Coronavirus disease 2019 (COVID-19) is a contagious disease caused by a new virus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). This disease became a pandemic and is being discussed around world because it has significant consequences on public health and global economy. Favipiravir is an anti-viral agent that selectively and potently inhibits RNA-dependent RNA polymerase (RdRp) from RNA viruses. Favipiravir was discovered through a screening list of chemicals with anti-viral activity against influenza virus by Toyama Chemical Coorperation. Use of Favipiravir in clinical trials has shown radiological improvement in lung CT scans and a faster viral clearance time than or antivirals.
Keywords:
Favirpiravir, anitiviral, RdRp, COVID-19Downloads
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