Preprint / Version 1

The Third Dose of the SARS-CoV-2 Vaccine: Why and for Whom?


  • Franco Borruto Professor of Obstetrics and Gynecology, Principality of Monaco
  • Ciro Comparetto Department of Obstetrics and Gynecology, San Paolo Private Clinic, Pistoia



The authors of this brief commentary give an update on the results of the last studies on the antibody response to the so-called “booster” administration of the Severe Acute Respiratory Syndrome (SARS)-CoronaVirus (CoV)-2 vaccines, with particular reference to the new “omicron” variant. A brief overview of the immunological response to this infection is also provided, with the advise that a serological test before the third dose of the vaccine is not recommended, as stated by the Food and Drug Administration (FDA).


SARS-CoV-2, CoVID-19, Vaccine


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