Preprint / Version 1

Bird’s Eye View on the Diagnosis, Treatment, & Prevention of the COVID-19 Outbreak




In December 2019, an outbreak of a new infectious disease occurred in Wuhan in the Hubei Province, China and spread across other Asian and non-Asian countries. The COVID-19 virus was known earlier as 2019 novel coronavirus (2019-nCoV) or the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). On February 12, 2020, the World Health Organization (WHO) officially named the disease caused by the novel coronavirus as Coronavirus Disease 2019 (COVID-19). Meanwhile, several independent research groups have identified that COVID-19 has a 79% genome sequence identity with SARS-CoV, the virus which caused a major outbreak in 2002–2003 when compared to MERS CoV. Even though some promising results have been achieved but Clinical studies of these candidate drugs need to be confirmed their safety and efficacy in the treatment of COVID-19. Till then the spread may be controlled only by following the strict quarantine protocols and preventive measures as there is no effective drug available for the treatment at this moment. This article gives a bird’s eye view about the current knowledge on the diagnosis, treatment, & prevention of the COVID-19 outbreak. Readers should renovate themselves regularly as the information about the virus is developing gradually at a greater rate.


COVID-19, Diagnosis, Treatment, Prevention


Download data is not yet available.


Mary A Lake, What we know so far: COVID-19 current clinical knowledge and research, Clinical Medicine 2020 Vol 20, No 2: 124–7

Tanu Singhal, A Review of Coronavirus Disease-2019 (COVID-19), The Indian Journal of Pediatrics (April 2020) 87(4):281–286,

CatrinSohrabia, ZaidAlsafib ,NiamhO'Neilla, MehdiKhanb,AhmedKerwanc, et al., World Health Organization declares global emergency : Are view of the 2019 novel coronavirus(COVID-19), International Journal of Surgery (2020) 71–76

Zi Yue Zu, Meng Di Jiang, Peng Peng Xu, Wen Chen, Qian Qian Ni, Guang Ming Lu, Long Jiang Zhang, Coronavirus Disease 2019 (COVID-19): A Perspective from China

Stuart Weston,a Matthew B. Friemana, COVID-19: Knowns, Unknowns, and Questions, American Society for Microbiology(2020) Volume 5

Jonas F Ludvigsson, Systematic review of COVID-19 in children show milder cases and a better prognosis than adults,

Jun Zheng, SARS-CoV-2: an Emerging Coronavirus that Causes a Global Threat, Int. J. Biol. Sci. 2020; 16(10): 1678-1685,

Kit?San Yuen, Zi ?Wei Ye, Sin?Yee Fung, Chi?Ping Chan and Dong?Yan Jin, SARS-CoV-2 and COVID-19: The most important research questions, Yuen et al. Cell Biosci (2020) 10:40,

Chih-Cheng Laia, Tzu-Ping Shihb, Wen-Chien Koc, Hung-Jen Tangd, Po-Ren Hsueh, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and corona virus disease-2019 (COVID-19): the epidemic and the challenges, International Journal of Antimicrobial Agents

Government of India, Ministry of Health & Family Welfare, Directorate General of Health Services, Revised Guidelines on Clinical Management of COVID–19.

S. KANNAN, P. SHAIK SYED ALI, A. SHEEZA, K. HEMALATHA, COVID-19 (Novel Coronavirus 2019) – recent trends, European Review for Medical and Pharmacological Sciences(2020); 24: 2006-2011

Buddhisha Udugama, Pranav Kadhiresan, Hannah N. Kozlowski et al., Diagnosing COVID-19: The Disease and Tools for Detection, ACS Pubication (2020),

Li Z, Yi Y, Luo X, Xiong N, Liu Y, Li S, Sun R, Wang Y et al., Development and clinical application of a rapid IgM-IgG combined antibody test for SARS-CoV-2 infection diagnosis, J Med Virol.(2020),

Diane Bronikowski, Nova Szoka, QSARS-COV-2 IGG/IGM RAPID TEST

Yan-Rong Guo, Qing-Dong Cao, Zhong-Si Hong, Yuan-Yang Tan et al., The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak – an update on the status, Military Medical Research (2020) 7:11,

Manli Wang, Ruiyuan Cao, Leike Zhang, Xinglou Yang et al., Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro, Cell Research (2020) 0:1–3,

C.A. Devaux, J.-M. Rolain and P. Colson et al., New insights on the antiviral effects of chloroquine against coronavirus: what to expect for COVID-19?, International Journal of Antimicrobial Agents

Jianjun Gao, Zhenxue Tian, Xu Yang, Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies, BioScience Trends. 2020; 14(1):72-73,

Franck Touret, Xavier de Lamballerie, Of chloroquine and COVID-19 , Antiviral Research 177 (2020) 104762,

Liying Dong, Shasha Hu, Jianjun Gao, Discovering drugs to treat coronavirus disease 2019 (COVID-19), Drug Discoveries & Therapeutics (2020); 14(1):58-60,

Shudong Zhu, Xialing Guo, Kyla Geary, and Dianzheng Zhang, Emerging Therapeutic Strategies for COVID-19 patients, Discoveries (Craiova). 2020 Jan-Mar; 8(1): e105,

H Li, Yeming Wang et al., Potential antiviral therapeutics for 2019 Novel Coronavirus, Chinese journal of tuberculosis and respiratory diseases (2020) 43:E002

Muhammad Adnan Shereena, Suliman Khana, Abeer Kazmic, Nadia Bashira, Rabeea Siddique, M.A. Shereen et al., COVID-19 infection: Origin, transmission, and characteristics of humancoronaviruses, Journal of Advanced Research 24 (2020) 91–98

Kai Duan, Bende Liu, Cesheng Li, Huajun Zhang, Ting Yu et al., Effectiveness of convalescent plasma therapy in severe COVID-19 patients, PNAS (2020) 1-7

Francesco Di Gennaro, Damiano Pizzol et al., Coronavirus Diseases (COVID-19) Current Status and Future Perspectives: A Narrative Review, Int. J. Environ. Res. Public Health 2020, 17, 2690,

Pengfei Sun, Xiaosheng Lu, Chao Xu, Wenjuan Sun, Bo Pan, Understanding of COVID-19 based on current evidence,

Rahman S, Bahar T. COVID-19: The New Threat, Int J Infect. 2020 ; 7(1):e102184.

John R., Marilyn D. Michelow, COVID-19 Infection: Implications for Perioperative and Critical Care Physicians, Anesthesiology (2020),

Luca Cristiani, Enrica Mancino et al., Will children reveal their secret? The coronavirus dilemma, Eur Respir J. (2020) Apr 2 : 2000749,

World Health Organization, Key considerations for repatriation and quarantine of travellers in relation to the outbreak of novel coronavirus 2019-nCoV, COVID-19 Travel Advice, 11 February 2020.